Hope for Treatment-Resistant Colorectal Cancer | Burzynski Clinic
Oct 18, 2025 | By: Burzynski Clinic
Colorectal cancer is the second leading cause of cancer deaths in the U.S. New research combining targeted therapy with sodium phenylbutyrate shows promising results for patients with advanced colorectal cancer who have exhausted standard treatments. This study highlights a hopeful step toward personalized, low-toxicity cancer care. Dive in to learn more about these innovative therapies.
Understanding Colorectal Cancer and Treatment Challenges
Colorectal cancer develops from tumors in the colon, rectum, or appendix and is often diagnosed late, making treatment more difficult. With about 150,000 new cases yearly in the U.S., understanding this disease is vital. Standard treatments include surgery, chemotherapy, and radiation, but options can be limited when these fail. This highlights the importance of research into alternatives like combining targeted therapy with sodium phenylbutyrate.
At Burzynski Clinic in Houston, TX, Dr. Stanislaw Burzynski and his team specialize in exploring innovative treatment options to provide new hope for patients facing advanced colorectal cancer.
What Is Sodium Phenylbutyrate?
Originally developed as a treatment for ureagenesis disorders, sodium phenylbutyrate (PB) is gaining attention for its potential in oncology. This compound acts as a histone deacetylase inhibitor and possesses structural features that can induce gene expression changes in cancer pathology, making it a candidate for combination therapies aimed at improving patient outcomes in difficult-to-treat cancers.
The Study: Combining Targeted Therapy with Sodium Phenylbutyrate
Research by Burzynski Clinic, published in the Journal of Cancer Therapy, studied combining targeted therapies with sodium phenylbutyrate in advanced colorectal cancer patients resistant to multiple treatments. This approach aimed to boost anti-tumor effects seen in earlier studies.
Key Findings:
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Improved Survival Rates: Preliminary results showed a significant increase in overall survival for patients receiving the combination therapy versus conventional treatments.
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Enhanced Tolerance: Patients experienced fewer side effects, suggesting a move toward gentler, low-toxicity cancer treatments.
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Mechanism of Action: The combination works by targeted therapy blocking cancer growth and sodium phenylbutyrate changing gene expression to overcome resistance in advanced cancer.
Implications for Future Cancer Treatment
This study by Burzynski Clinic signals a shift toward personalized colorectal cancer treatment, considering tumor genetics and patient tolerance. Combining therapies like PB enables tailored plans, offering new hope for those with limited options.
Patient-Centric Approach to Care
A patient-focused approach is key in cancer care, emphasizing emotional support alongside treatment. At Burzynski Clinic, patients are active partners in their journey, receiving education and personalized support to boost resilience, satisfaction, and treatment success.
Comprehensive Support for Healing and Wellness
At Burzynski Clinic, Dr. Burzynski and his team believe cancer care extends beyond medical treatments to address the whole person’s wellbeing. Alongside innovative therapies, our patient-centered approach includes:
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Emotional and Psychological Support: Navigating cancer is challenging, and emotional resilience plays a vital role. We provide counseling and education to empower patients as active partners in their care, helping them stay motivated and engaged throughout their journey.
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Nutritional Counseling: Proper nutrition supports the body’s ability to heal and tolerate treatments. Our tailored nutritional programs aim to reduce side effects, boost immune function, and improve overall quality of life.
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Integrative Therapies: Pain management, physical therapy, and stress reduction techniques such as mindfulness and relaxation therapy are offered to enhance comfort and wellbeing during treatment.
By combining these elements, Dr. Burzynski creates a holistic care environment that supports patients physically, emotionally, and mentally — helping them build strength and resilience from diagnosis through recovery.
Hope in Action: Progress Through Research
The path to discovering new cancer therapies is filled with challenges. Each study, like the one discussed, reflects the shared commitment of researchers, oncologists, and patients striving toward a future where cancer can be effectively managed. Through dedicated research and a deeper understanding of cancer biology, Dr. Burzynski and his team at Burzynski Clinic are developing innovative strategies that have the potential to significantly improve patient outcomes.
Take the Next Step in Your Care
So now what? Engage with your healthcare team to explore how novel therapies could fit into your journey. Remember, you are not alone—together, we focus on progress, strength, and the potential waiting ahead. As we embrace the spirit of hope, each breakthrough reminds us that tomorrow holds promise, even amidst struggle.
Schedule a consultaion at Burzynski Clinic in Houston, and take the first step towards a personalized future in your cancer care journey with Dr. Burzynski and his team.